Recombinant tissue type plasminogen activator treatment of thrombosed mitral valve prosthesis during pregnancy
نویسندگان
چکیده
منابع مشابه
Recombinant tissue type plasminogen activator treatment of thrombosed mitral valve prosthesis during pregnancy.
PURPOSE Prosthetic heart valve thrombosis occurring during pregnancy is a life-threatening complication. Surgical treatment requires clot removal under cardiopulmonary bypass (CPB) and carries a high mortality. We describe the successful use of thrombolytic therapy for recurrent thrombosed valve prosthesis in a pregnant patient. CLINICAL FEATURES A 32-yr-old patient whose pregnancy was compli...
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Background: Thrombolytic therapy is the recommended treatment of acute ischemic stroke. It is crucial to evaluate the treatment results with recombinant Tissue Plasminogen Activator (r-TPA) in patients with acute stroke. Objectives: This study aimed to evaluate treatment outcomes with r-TPA in patients with acute stroke in a referral stroke center in Iran. Materials & Methods: In this retrosp...
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Low molecular size additives such as L-arginine and the redox compounds have been used both in the culturemedium and in vitro refolding to increase recombinant proteins production. Additives increase proteinrefolding and yield of active proteins by suppressing aggregate formation or enhancing refolding process.In this work, a comparative study was performed on refolding of rec...
متن کاملSuccessful thrombolysis of a thrombosed prosthetic mitral valve using a synthetic tissue plasminogen activator: a case report
INTRODUCTION Prosthetic valve thrombosis is a rare but life-threatening condition that requires careful evaluation and prompt treatment. While surgical intervention remains the gold standard, thrombolytic therapy is now emerging as a potential substitute. Various thrombolytic treatments including streptokinase, urokinase and recombinant tissue plasminogen activators have been reported with vari...
متن کاملSuccessful thrombolysis of mitral valve prosthesis by streptokinase during pregnancy.
A 37 year old female patient presented with the clinical picture of pulmonary edema while pregnant (13 weeks). Eight years earlier she underwent mitral valve replacement because of rheumatic mitral incompetence using bileaflet StJude prosthesis. Her oral anticoagulation maintenance therapy (Coumadin) was discontinued by her physician and shifted to subcutaneous unfractionated heparin 10 days pr...
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ژورنال
عنوان ژورنال: Canadian Journal of Anaesthesia
سال: 1997
ISSN: 0832-610X,1496-8975
DOI: 10.1007/bf03013388